I am a 32-year-old woman dating a very nice man my age. My boyfriend and I have been dating for just about a year and we are serious about each other. He has severe asthma and has to be on high doses of steroids during and for a long time after a flare-up. The problem is these steroids have a terrible effect on him: he breaks out in acne; he is irritable and loses control of his temper; his appetite is voracious; he puffs out in his stomach and face.

The problem with his temper and irritability is what most bothers me, it is as if he has a completely different personality and sometimes it is frightening. We have talked to his doctor who says that these steroids are the drug of choice and if he does not take them as an outpatient, he would have to be hospitalized and put on the same medications.

As I said, his personality can be frightening on the steroids, but I have seen my boyfriend in an asthma attack which is even more frightening. I once talked to a therapist about this problem. Maybe I should have been more careful in choosing a therapist, but this woman came from a feminist perspective and in a sense told me that I should break up with this man. I don't think that this is the solution since I love him very much and I know that off steroids he is the man I love.

Could you possibly tell me the interactive effects of Zoloft (the anti-depressant) and MDMA (Ecstasy)?

I am a teenage girl currently taking Adderall (20 mg) to treat my ADHD. My question: does taking this medication affect sexual wantings or behavior? I am supposed to start taking it at 7:00am so it will wear out at about 9:00 or 9:30pm. Since I go out later at night, my medicine is usually worn off before I engage in any kind of sexual activity. But sometimes on weekends I wake up late and have to take it at later times such as 12:00 or 1:00pm. Since then it will not wear off until after I go out, would being on Adderall affect my sexual behavior? I feel like I am less "horny" when on Adderall and sex is worse because of the lack of my desires. Does this have anything to do with my medicine or is it just a coincidence?

I originally took a muscle relaxer because I was experiencing very bad back pain and could not sleep. I was not prescribed the muscle relaxers. My friend suggested I take one of hers. So I did, and now I will take one sometimes before bed if I can't fall asleep or if I want to actually just relax. It makes me just want to sleep, and I feel really calm after taking one. Is this bad that I take them for this reason? What are the side effects? Is it harmful?

I have been taking between 5 and 10 mgs of methadone daily. I cannot seem to stop. Every time I try, I get very, very depressed and experience abdominal pain, chills, hot flashes, and sleeplessness. The depression and tremendous anxiety are intolerable and I end up taking more to avoid it. Question: Am I harming my body and/or mind with this stuff? How can I get off without the horrible feelings?

My friend and I snorted a 10 bag each of heroin. Our heads began to feel heavy after ten minutes. Soon we entered into a dream world in which we hallucinated heavily. We talked to people who did not exist and we were very confused. I could not remember anything about who I was. I only remember certain parts of the four-hour trip that followed but I felt like I was on mushrooms for about two days. We could not read for that amount of time (nothing was in focus). What do you think we took? PCP? Bad synthetic heroin?

Recently I have started snorting Ritalin and Adderall (not at the same time though). I have found that the effects closely resemble that of snorting cocaine, but are not quite as intense. I really like doing this, because it's much cheaper than buying coke. However, I was wondering exactly how dangerous this might be, if even at all, considering it's a prescribed drug and I never snort more than the average dose that you would take orally. If you could tell me what the danger in doing this is and what I might possibly be doing to my body, that would be great.

I'm thinking about trying heroin. However, this prospect makes me nervous because of all the media reports of people becoming so quickly addicted to it, wasting away, and even dying from overdoses. Any advice?