How do marijuana and Prozac interact?

I have two friends who were recently diagnosed with depression. They were both prescribed Prozac by their respective doctors. Both of them are heavy marijuana users and both failed to mention that to their doctors. One has been on Prozac for two months and the other for six weeks. I have noticed that their behavior has become strange: mood swings, paranoia, oversleeping, fatigue. They continue taking their Prozac (20 mg a day) and continue smoking pot. I am afraid that there might be some negative interaction between the substances, one being an antidepressant and the other a depressant. Can you provide some insight?


Is hot sauce the source of my anal aggravation?

I enjoy my spicy foods. In fact, the spicier, the better. If I break a sweat when I'm eating, I've made a successful meal. I'm extremely active, physically, and I rarely get sick. I don't use tobacco, but I drink coffee daily. I average about two bowel movements a day, and I've found within the last week or so, blood on my toilet paper when I wipe my arse. Can the blood be caused by my spicy foods? I had my wife check out the area in question, and she says that it doesn't look like my rectum was bleeding (but it sure felt like it for about two minutes). I just wanted to know if the spicy foods can actually cause bleeding around there, and if so, does this mean that the bleeding could be caused in other places within my digestive system?